SCHEMBL7326813

SCHEMBL7326813

O=C(C1=CSC=CN1C(=O)CCCC1Cc2ccc([N+](=O)[O-])cc2C1)N1CCSC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PREP P48147 8/20 0.37
DPP4 P27487 6/20 0.37
DPP7 Q9UHL4 2/20 0.37
PNMT P11086 3/20 0.33
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
ADRA2A P08913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7359386 0.84 PREP (0.45) PREPDPP4DPP7
SCHEMBL7349204 0.77 PREP (0.55) PREPDPP4DPP7
SCHEMBL7329968 0.70 PREP (0.46) PREP
SCHEMBL9791373 0.69 PREP (0.46) PREP
SCHEMBL7354558 0.66 PREP (0.41) PREPDPP4DPP7
SCHEMBL7354544 0.66 PREP (0.51) PREP
SCHEMBL7323490 0.65 PREP (0.46) PREPDPP4DPP8DPP9
SCHEMBL8667327 0.65 PNMT (0.50) PNMTADRA2A
SCHEMBL9556413 0.65 DPP4 (0.63) DPP4DPP7
SCHEMBL7325498 0.65 PREP (0.42) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed