Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7336666 | 0.99 | GRIN2B (0.59) | GRIN2BSIGMAR1GRIN1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7327548 | 0.96 | GRIN2B (0.60) | GRIN2BSIGMAR1GRIN1 | |
| Hydrochloric Acid SCHEMBL7328949 | 0.96 | GRIN2B (0.60) | GRIN2BSIGMAR1GRIN1 | |
| Hydrochloric Acid SCHEMBL7327564 | 0.96 | GRIN2B (0.60) | GRIN2BSIGMAR1GRIN1 | |
| Hydrochloric Acid SCHEMBL7328559 | 0.96 | GRIN2B (0.60) | GRIN2BSIGMAR1GRIN1 | |
| Hydrochloric Acid SCHEMBL7326697 | 0.96 | GRIN2B (0.60) | GRIN2BSIGMAR1GRIN1 | |
| Hydrochloric Acid SCHEMBL7328346 | 0.96 | GRIN2B (0.60) | GRIN2BSIGMAR1GRIN1 | |
| SCHEMBL7327888 | 0.94 | GRIN2B (0.58) | GRIN2BSIGMAR1DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7335303 | 0.93 | GRIN2B (0.57) | GRIN2BSIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL7328335 | 0.87 | DRD2 (0.61) | GRIN2BDRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196454-A | METHOD OF TREATING DISORDERS OF THE DOPAMINERGIC SYSTEMS USING 2,5-DIAMINOTETRALINES | BOEHRINGER INGELHEIM KG (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |