Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.38 |
| ▸ | PRKCG | P05129 | 3/20 | 0.38 |
| ▸ | PRKCB | P05771 | 3/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | PRKCH | P24723 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 3/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | PRKACG | P22612 | 2/20 | 0.38 |
| ▸ | PRKACB | P22694 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327666 | 0.86 | CHRM1 (0.46) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7325041 | 0.80 | ROCK2 (0.36) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7321039 | 0.80 | COMT (0.40) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL5083072 | 0.80 | ROCK2 (0.49) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7324789 | 0.79 | COMT (0.43) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7317797 | 0.78 | COMT (0.37) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL4728648 | 0.78 | ROCK2 (0.45) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL13513879 | 0.77 | PRKCD (0.65) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7329002 | 0.77 | COMT (0.52) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7316968 | 0.77 | COMT (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |