Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316968 | 0.85 | COMT (0.46) | ALDH1A1COMT | |
| SCHEMBL7321039 | 0.82 | COMT (0.40) | ROCK2ROCK1PRKXPRKCEPRKCD | |
| SCHEMBL7317797 | 0.81 | COMT (0.37) | ROCK2ROCK1PRKXPRKCEPRKCD | |
| SCHEMBL7327006 | 0.80 | ROCK2 (0.39) | ROCK2ROCK1PRKXPRKCEPRKCD | |
| SCHEMBL7319338 | 0.77 | ROCK2 (0.39) | ROCK2ROCK1PRKXPRKCEPRKCD | |
| SCHEMBL7325026 | 0.74 | MAPT (0.33) | ROCK2ROCK1COMTHTR7HTR1A | |
| SCHEMBL5083072 | 0.74 | ROCK2 (0.49) | ROCK2ROCK1PRKXPRKCEPRKCD | |
| SCHEMBL7360634 | 0.73 | CHRM1 (0.42) | ALDH1A1LMNACOMTCHRM1 | |
| SCHEMBL7326984 | 0.73 | CHRM1 (0.46) | ROCK2ROCK1PRKXPRKCEPRKCD | |
| SCHEMBL7327081 | 0.72 | ROCK2 (0.57) | ROCK2ROCK1PRKXPRKCEPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |