Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031740 | 0.84 | DPP4 (0.38) | PDCD1LG2CD274KDM4EPTGS2THPO | |
| SCHEMBL30717674 | 0.79 | MME (0.47) | ACEMMEMAPT | |
| SCHEMBL29564354 | 0.79 | ACE (0.51) | ACEPTGS1GSTK1PDCD1LG2CD274 | |
| SCHEMBL30288039 | 0.79 | ACE (0.51) | ACEPTGS1GSTK1PDCD1LG2CD274 | |
| SCHEMBL9303123 | 0.79 | DPP4 (0.34) | PDCD1LG2CD274PAX8 | |
| SCHEMBL30288027 | 0.79 | ACE (0.51) | ACEPTGS1GSTK1PDCD1LG2CD274 | |
| SCHEMBL28081216 | 0.78 | NMT1 (0.46) | NMT2NMT1 | |
| SCHEMBL16770237 | 0.77 | ACE (0.53) | ACEPTGS1GSTK1PDCD1LG2CD274 | |
| SCHEMBL29939666 | 0.76 | ACE (0.50) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL6048582 | 0.75 | CTSC (0.32) | PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341603-A2 | Atrial peptide derivatives | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |