Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318270 | 0.94 | REN (0.51) | RENCTSDCTSE | |
| SCHEMBL10772344 | 0.91 | REN (0.54) | REN | |
| SCHEMBL10579981 | 0.84 | REN (0.56) | REN | |
| SCHEMBL10579119 | 0.84 | REN (0.56) | REN | |
| SCHEMBL9694627 | 0.82 | REN (0.54) | REN | |
| SCHEMBL9694155 | 0.82 | REN (0.54) | REN | |
| SCHEMBL9694227 | 0.82 | REN (0.54) | REN | |
| SCHEMBL7328163 | 0.81 | REN (0.59) | REN | |
| SCHEMBL9876108 | 0.78 | REN (0.56) | REN | |
| SCHEMBL9876104 | 0.78 | REN (0.56) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237202-A2 | Novel renin inhibiting peptides having a dihydroxyethylene isostere transition state insert | THE UPJOHN COMPANY (US) | 1987-09-16 | — | — | EP | claimed |
| WO-1987005302-A1 | NOVEL RENIN-INHIBITING PEPTIDES HAVING A DIHYDROXYETHYLENE ISOSTERE TRANSITION STATE INSERT | THE UPJOHN COMPANY (US) | 1987-09-11 | — | — | WO | claimed |