SCHEMBL10772344

CC[C@H](C)[C@H](N)C(=O)N(C(=O)c1ccccn1)C(=O)[C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	18/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10579119	0.93	REN (0.56)	REN
SCHEMBL10579981	0.93	REN (0.56)	REN
SCHEMBL7327057	0.91	REN (0.48)	REN
SCHEMBL7318270	0.84	REN (0.51)	REN
SCHEMBL7325297	0.82	REN (0.46)	REN
SCHEMBL7318770	0.82	REN (0.49)	REN
SCHEMBL10771117	0.76	REN (0.53)	REN
SCHEMBL7335731	0.75	CTSS (0.47)	REN
SCHEMBL7323845	0.74	REN (0.58)	REN
SCHEMBL9677828	0.74	REN (0.44)	REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0237202-A2	Novel renin inhibiting peptides having a dihydroxyethylene isostere transition state insert	THE UPJOHN COMPANY (US)	1987-09-16	—	—	EP	claimed