Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 12/20 | 0.57 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327118 | 1.00 | CCR2 (0.57) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL7322614 | 0.97 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL7320500 | 0.97 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL7322622 | 0.97 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL7320505 | 0.97 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL2462209 | 0.93 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL29418355 | 0.93 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL203904 | 0.93 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL203905 | 0.93 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA | |
| SCHEMBL2460843 | 0.93 | CCR2 (0.60) | CCR2CCR1CCR5CXCR4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |