Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | ESR1 | P03372 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.73 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.73 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479457 | 1.00 | HSD17B10 (0.73) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL30520180 | 1.00 | HSD17B10 (0.73) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL6479462 | 1.00 | HSD17B10 (0.73) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL5020108 | 1.00 | HSD17B10 (0.73) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL7348790 | 1.00 | HSD17B10 (0.73) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL10964457 | 0.87 | POLB (0.54) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL10339936 | 0.87 | POLB (0.54) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL7324499 | 0.87 | TDP1 (0.54) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL10636932 | 0.87 | POLB (0.54) | HSD17B10HPGDKDM4EPOLBTDP1 | |
| SCHEMBL10339937 | 0.87 | POLB (0.54) | HSD17B10HPGDKDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116429930-A | Method for detecting diltiazem hydrochloride intermediate and related substances thereof | 武汉爱民制药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-100364540-C | Pharmaceutical use of (2s-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one for treating hepatitis | UNIV BEIJING (CN) | 2008-01-30 | — | — | CN | disclosed |
| CN-100364540-C | Pharmaceutical use of (2s-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one for treating hepatitis | UNIV BEIJING (CN) | 2008-01-30 | — | — | CN | disclosed |
| CN-1850088-A | Pharmaceutical use of (2s-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one for treating hepatitis | UNIV BEIJING (CN) | 2006-10-25 | — | — | CN | disclosed |
| CN-1850088-A | Pharmaceutical use of (2s-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one for treating hepatitis | UNIV BEIJING (CN) | 2006-10-25 | — | — | CN | disclosed |
| US-4902684-A | Benzazepine and benzothiazepine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1990-02-20 | — | — | US | disclosed |
| WO-1989012633-A1 | BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | E.R. SQUIBB & SONS, INC. (US) | 1989-12-28 | — | — | WO | disclosed |