Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7319914 | 0.99 | KMT2A (0.53) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL7330875 | 0.94 | F10 (0.52) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL7321079 | 0.87 | KMT2A (0.51) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL21771940 | 0.80 | KMT2A (0.76) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL21771978 | 0.80 | KMT2A (0.67) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL21771975 | 0.78 | KMT2A (0.55) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL16685068 | 0.78 | KMT2A (0.77) | KMT2ANPC1RAB9ANR1I2LMNA | |
| SCHEMBL7333430 | 0.78 | PRSS1 (0.57) | KMT2ASMN1; SMN2F10MAPTF2 | |
| SCHEMBL7329213 | 0.78 | ESR1 (0.52) | KMT2ANPC1RAB9ASMN1; SMN2F10 | |
| SCHEMBL18668301 | 0.77 | MAPT (0.55) | KMT2ANPC1RAB9ANR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |