Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330746 | 0.92 | FTO (0.48) | ESR1ESR2SLC6A3PARP10KMT2A | |
| SCHEMBL7321924 | 0.90 | SLC6A3 (0.47) | ESR1ESR2SLC6A3PARP10KMT2A | |
| Bicarbonate SCHEMBL7333292 | 0.89 | SLC6A3 (0.46) | ESR1ESR2SLC6A3PARP10KMT2A | |
| SCHEMBL7326063 | 0.87 | SLC6A3 (0.62) | SLC6A3PARP10KMT2AMAPTPRSS1 | |
| SCHEMBL7331841 | 0.85 | ESR1 (0.50) | ESR1ESR2SLC6A3PARP10KMT2A | |
| Bromide SCHEMBL7330269 | 0.84 | ESR1 (0.49) | ESR1ESR2SLC6A3PARP10KMT2A | |
| SCHEMBL7330751 | 0.83 | SLC6A3 (0.44) | ESR1ESR2SLC6A3PARP10KMT2A | |
| SCHEMBL7324828 | 0.83 | FTO (0.47) | SLC6A3PARP10KMT2AMAPTPRSS1 | |
| SCHEMBL7333430 | 0.82 | PRSS1 (0.57) | PARP10KMT2AMAPTSMN1; SMN2PRSS1 | |
| SCHEMBL7324570 | 0.81 | MAPT (0.61) | KMT2AMAPTPRSS1ACRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |