SCHEMBL7327400

SCHEMBL7327400

CCOC(=CC=C(OCC)O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7327396 1.00 GLO1 (0.32) GLO1ALDH1A1LMNAHSD17B10
SCHEMBL10489185 0.87
SCHEMBL10489190 0.87
SCHEMBL5316360 0.85 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10
SCHEMBL5316362 0.85 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10
SCHEMBL10489199 0.82
SCHEMBL10489201 0.82
SCHEMBL9775012 0.81
SCHEMBL9775008 0.81
SCHEMBL8776721 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384380-B1 Novel peptide derivatives and their pharmaceutical use JAPAN TOBACCO INC (JP) 1996-06-19 EP disclosed
US-5151497-A Central nervous system disorders, antidepressants, epilepsy and cognition activators JAPAN TOBACCO INC. (JP) 1992-09-29 US disclosed
EP-0384380-A2 Novel peptide derivatives and their pharmaceutical use JAPAN TOBACCO INC. (JP) 1990-08-29 EP disclosed