Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9715221 | 0.99 | HPGD (0.45) | HPGDALDH1A1MEN1KMT2APRSS1 | |
| SCHEMBL16450930 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTF10 | |
| SCHEMBL15907989 | 0.82 | ALDH1A1 (0.48) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3686150 | 0.82 | ALDH1A1 (0.51) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20133945 | 0.82 | ALDH1A1 (0.43) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL300884 | 0.81 | CA12 (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7910504 | 0.81 | ALDH1A1 (0.43) | HPGDALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7910402 | 0.81 | ALDH1A1 (0.43) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27807368 | 0.80 | PARP10 (0.42) | HPGDALDH1A1KMT2AF2MAPT | |
| SCHEMBL9715241 | 0.80 | F2 (0.38) | PRSS1F2PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343894-B1 | BENZAMIDE PROTEASE INHIBITORS | PFIZER INC. (US) | 1992-06-10 | — | — | EP | disclosed |
| US-4948901-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4948891-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0343894-A1 | Benzamide protease inhibitors | PFIZER INC. (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4874864-A | ANTIPLASMIN, ANTITHROMBIN AGENTS | PFIZER INC. (US) | 1989-10-17 | — | — | US | disclosed |