Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243002 | 1.00 | MEN1 (0.47) | MEN1KMT2AL3MBTL1ALDH1A1ADH1C | |
| Hydrochloric Acid SCHEMBL7333956 | 0.98 | MEN1 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1ADH1C | |
| SCHEMBL7324391 | 0.98 | MEN1 (0.44) | MEN1KMT2AL3MBTL1ALDH1A1ADH1C | |
| SCHEMBL8388644 | 0.90 | MEN1 (0.37) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3205284 | 0.87 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL17337970 | 0.87 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL19962868 | 0.85 | TDP1 (0.48) | MEN1KMT2AALDH1A1ADH1CADH1A | |
| SCHEMBL17338031 | 0.85 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL17337986 | 0.85 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL11186154 | 0.85 | TDP1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221665-A | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0369391-A2 | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |