Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 16/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726146 | 0.89 | CTSS (0.54) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL9831219 | 0.89 | CTSS (0.54) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL10386880 | 0.89 | CTSS (0.54) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL3606572 | 0.88 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL3606578 | 0.88 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL3606570 | 0.88 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7284721 | 0.88 | CTSS (0.55) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7331578 | 0.88 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7431703 | 0.87 | REN (0.47) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL10610618 | 0.87 | REN (0.47) | CTSSCTSKRENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |