Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11875312 | 0.90 | OPRK1 (0.55) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL552965 | 0.90 | DRD3 (0.71) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL4269278 | 0.90 | OPRK1 (0.55) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL28327056 | 0.88 | DRD3 (0.69) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL8074986 | 0.88 | OPRK1 (0.53) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL10701253 | 0.87 | OPRM1 (0.63) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL11197923 | 0.85 | HRH3 (0.59) | DRD2DRD3OPRM1OPRD1DRD1 | |
| Hydrochloric Acid SCHEMBL9324806 | 0.83 | HRH3 (0.57) | OPRM1OPRD1OPRK1BCHE | |
| SCHEMBL12128296 | 0.82 | DRD3 (0.68) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| (Chloromethyl)Benzene SCHEMBL7216279 | 0.80 | DRD3 (0.50) | DRD2DRD3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596891-B1 | AMINOALKYL-SUBSTITUTED 2-AMINO-5-MERCAPTOTHIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 1998-08-12 | — | — | EP | disclosed |
| US-5401743-A | Treatment of high blood pressure, Parkinson*s disease, schizophrenia, dopamine receptors | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| EP-0596891-A1 | AMINOALKYL-SUBSTITUTED 2-AMINO-5-MERCAPTOTHIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1994-05-18 | — | — | EP | disclosed |
| WO-1992022542-A1 | AMINOALKYL-SUBSTITUTED 2-AMINO-5-MERCAPTOTHIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | WO | disclosed |