Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 14/20 | 0.33 |
| ▸ | CNR2 | P34972 | 14/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287792 | 0.89 | ACACB (0.39) | PTGS2CNR1CNR2KCNH2SLC6A3 | |
| SCHEMBL13039843 | 0.85 | PTGS2 (0.37) | PTGS2CNR1CNR2KCNH2SLC6A3 | |
| SCHEMBL13076982 | 0.83 | PTGS2 (0.35) | PTGS2CNR1CNR2KCNH2SLC6A3 | |
| SCHEMBL734171 | 0.83 | PTGS2 (0.39) | PTGS2CNR1CNR2KCNH2MDM2 | |
| SCHEMBL13167961 | 0.81 | OPRM1 (0.37) | PTGS2CNR1 | |
| SCHEMBL13052290 | 0.81 | PTGS2 (0.39) | PTGS2SLC6A3MAPTHPGD | |
| SCHEMBL12214969 | 0.81 | PTGS2 (0.36) | PTGS2CNR1CNR2KCNH2SLC6A3 | |
| SCHEMBL12362048 | 0.79 | PTGS2 (0.37) | PTGS2CNR1CNR2KCNH2MAPT | |
| SCHEMBL12231716 | 0.78 | PTGS2 (0.36) | PTGS2CNR1CNR2KCNH2MAPT | |
| SCHEMBL13070291 | 0.78 | PTGS2 (0.35) | PTGS2CNR1CNR2KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138119-B2 | Alkoxyalkyl spirocyclic tetramic acids and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20090215624-A1 | Alkoxyalkyl Spirocyclic Tetramic Acids and Tetronic Acids | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215624-A1 | Alkoxyalkyl Spirocyclic Tetramic Acids and Tetronic Acids | DDT, TBCD, TBCA | PTGS2 4449/4885CNR1 1389/4885CNR2 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.