Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 12/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7328948 | 0.85 | DRD4 (0.54) | DRD4KDM4EHRH3 | |
| SCHEMBL27991036 | 0.81 | DRD4 (0.62) | DRD4HRH3SIGMAR1 | |
| Oxalic Acid SCHEMBL9528825 | 0.81 | KDM4E (0.53) | KDM4EHTTHRH3 | |
| SCHEMBL7328953 | 0.78 | DRD4 (0.57) | DRD4HRH3 | |
| SCHEMBL19381943 | 0.76 | DRD4 (0.67) | DRD4HRH3SIGMAR1 | |
| Oxalic Acid SCHEMBL9699030 | 0.75 | KDM4E (0.56) | KDM4EHTTHRH3 | |
| SCHEMBL9527998 | 0.74 | MEN1 (0.51) | HTTHRH3 | |
| SCHEMBL9372865 | 0.74 | SIGMAR1 (0.49) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9374823 | 0.73 | SIGMAR1 (0.48) | SIGMAR1 | |
| Oxalic Acid SCHEMBL7327098 | 0.72 | SSTR5 (0.51) | KDM4EHTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | disclosed |