Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202038 | 0.86 | NPC1 (0.49) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL30172583 | 0.85 | KDM4E (0.64) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL662652 | 0.85 | KDM4E (0.64) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL28267403 | 0.84 | KDM4E (0.62) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11329279 | 0.84 | KDM4E (0.62) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL1613027 | 0.82 | KDM4E (0.67) | KDM4ESMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL5202032 | 0.82 | NCOA1 (0.65) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL27632452 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL28164670 | 0.81 | L3MBTL1 (0.63) | KDM4ELMNASMN1; SMN2HTTNPC1 | |
| SCHEMBL1898779 | 0.79 | KDM4E (0.76) | AKR1C3AKR1C2AKR1C1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115652144-B | Corrosion-resistant aluminum-zinc alloy added with rare earth elements and preparation method thereof | 江苏同生特钢制造有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115652144-A | Corrosion-resistant aluminum-zinc alloy added with rare earth elements and preparation method thereof | 江苏同生特钢制造有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115652144-B | Corrosion-resistant aluminum-zinc alloy added with rare earth elements and preparation method thereof | 江苏同生特钢制造有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115652144-A | Corrosion-resistant aluminum-zinc alloy added with rare earth elements and preparation method thereof | 江苏同生特钢制造有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-5935970-A | Use of imidazo 1,5-a!quinolones as neuroprotective agents | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0729469-B1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | UPJOHN CO (US) | 1998-09-23 | — | — | EP | disclosed |
| US-RE35840-E | Imidazo 1,5-a!quinolines for treatment of anxiety and sleep disorders | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0833638-A1 | USE OF IMIDAZO 1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5594140-A | Imidazo[1,5-A]quinolines for treatment of anxiety and sleep disorders | THE UPJOHN COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1997000074-A1 | USE OF IMIDAZO[1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |
| EP-0729469-A1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014020-A1 | IMIDAZO[1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | THE UPJOHN COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |
| US-4265892-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4154831-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4067979-A | Cephalosporins having an α-acyloxyacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4041161-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |