Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26011205 | 0.95 | — | — | |
| SCHEMBL30917693 | 0.95 | — | — | |
| SCHEMBL26011209 | 0.95 | — | — | |
| SCHEMBL84792 | 0.95 | — | — | |
| SCHEMBL178545 | 0.95 | — | — | |
| SCHEMBL1086946 | 0.95 | — | — | |
| Bromide SCHEMBL7595850 | 0.93 | POLB (0.48) | POLBL3MBTL1CYP1A2CHRNB2CHRNA4 | |
| Iodide SCHEMBL28525835 | 0.93 | POLB (0.48) | POLBL3MBTL1CYP1A2CHRNB2CHRNA4 | |
| Lithium Ion SCHEMBL7328185 | 0.89 | POLB (0.45) | POLBL3MBTL1CYP1A2CHRNB2CHRNA4 | |
| SCHEMBL25262256 | 0.88 | CYP1A2 (0.55) | POLBL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989012633-A1 | BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | E.R. SQUIBB & SONS, INC. (US) | 1989-12-28 | — | — | WO | disclosed |