Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | CTRC | Q99895 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543477 | 0.81 | F2 (0.62) | F2F10PRSS2CTRC | |
| SCHEMBL7329198 | 0.79 | F2 (0.66) | F2F10PRSS2CTRC | |
| SCHEMBL8650120 | 0.79 | F2 (0.51) | F2F10PRSS2CTRC | |
| SCHEMBL7332517 | 0.77 | F2 (0.54) | F2PRSS2CTRCALDH1A1 | |
| SCHEMBL7435413 | 0.73 | F2 (0.74) | F2F10PRSS2CTRC | |
| SCHEMBL20758809 | 0.73 | KMT2A (0.60) | ALDH1A1TDP1LTB4RLTB4R2 | |
| SCHEMBL20083681 | 0.71 | ALDH1A1 (0.61) | ALDH1A1TDP1 | |
| SCHEMBL7442037 | 0.71 | F2 (0.58) | F2F10PRSS2CTRC | |
| SCHEMBL7444372 | 0.71 | F2 (0.53) | F2F10 | |
| SCHEMBL6749570 | 0.70 | F2 (0.59) | F2F10PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |