Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272393 | 0.80 | SMN1; SMN2 (0.45) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL10272389 | 0.79 | GRM5 (0.45) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL7996902 | 0.78 | SMN1; SMN2 (0.41) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL7363507 | 0.78 | MAPT (0.46) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL9693096 | 0.77 | MAPT (0.46) | KDM4EMAPTSMN1; SMN2LMNAPABPC1 | |
| SCHEMBL7996906 | 0.75 | SMN1; SMN2 (0.46) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL11066127 | 0.75 | SMN1; SMN2 (0.45) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL1545782 | 0.74 | LMNA (0.45) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL15926459 | 0.74 | SMN1; SMN2 (0.44) | KDM4EGAASMN1; SMN2LMNAPABPC1 | |
| SCHEMBL1016251 | 0.74 | HTT (0.48) | KDM4EGAAMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556008-B1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5461062-A | Psychotropic agent as antianxiety agent, anesthesia antagonistic agent | SHIONOGI & CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5378848-A | Benzodiazepine agonist, psychotropic, antianxiety, cerebral function activator, anesthesia atagonist | SHIONOGI & CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0556008-A1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |