Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018183 | 0.88 | RAB9A (0.47) | GRM5CYP1A2CYP3A4CACNA1CSCN5A | |
| SCHEMBL10209168 | 0.84 | SLC6A15 (0.41) | GRM5CYP1A2CYP3A4CACNA1CSCN5A | |
| SCHEMBL1016251 | 0.84 | HTT (0.48) | GRM5CYP1A2CYP3A4CACNA1CSCN5A | |
| SCHEMBL1017250 | 0.82 | PIK3CA (0.52) | SMN1; SMN2L3MBTL1RXFP1KDM4EPIK3R1 | |
| SCHEMBL15779200 | 0.82 | RAB9A (0.47) | GRM5CYP1A2CYP3A4CACNA1CSCN5A | |
| SCHEMBL11066127 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1KDM4EPIK3R1PIK3CA | |
| SCHEMBL7328252 | 0.79 | KDM4E (0.43) | GRM5CYP1A2CYP3A4CACNA1CSCN5A | |
| SCHEMBL15926459 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1RXFP1KDM4ERAB9A | |
| SCHEMBL15309449 | 0.76 | ABHD6 (0.49) | SMN1; SMN2L3MBTL1RXFP1KDM4EGAA | |
| SCHEMBL10272393 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1RXFP1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053201-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053201-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC1, HDAC2 | GRM5 483/4885CYP1A2 1215/4885CYP3A4 3110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.