Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.78 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751309 | 1.00 | HTR6 (0.78) | HTR6HTR2CADRA2A | |
| SCHEMBL732830 | 1.00 | HTR6 (0.78) | HTR6HTR2CADRA2A | |
| SCHEMBL730226 | 0.85 | HTR6 (0.77) | HTR6HTR2CADRA2A | |
| SCHEMBL730225 | 0.85 | HTR6 (0.77) | HTR6HTR2CADRA2A | |
| SCHEMBL13442963 | 0.85 | HTR6 (0.77) | HTR6HTR2CADRA2A | |
| SCHEMBL14290574 | 0.81 | HTR6 (0.76) | HTR6HTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL3616472 | 0.81 | HTR6 (0.78) | HTR6HTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL3616474 | 0.81 | HTR6 (0.78) | HTR6HTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL3613619 | 0.80 | HTR6 (0.77) | HTR6HTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL3615615 | 0.80 | HTR6 (0.77) | HTR6HTR2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069378-A1 | SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-03-18 | — | — | US | claimed |
| EP-1884515-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | Laboratorios del Dr. Esteve S.A. (ES) | 2008-02-06 | — | — | EP | claimed |
| US-20080027073-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-01-31 | — | — | US | claimed |
| US-8138210-B2 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-03-20 | — | — | US | disclosed |
| US-20100069378-A1 | SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-03-18 | — | — | US | disclosed |
| EP-1884515-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | Laboratorios del Dr. Esteve S.A. (ES) | 2008-02-06 | — | — | EP | disclosed |
| US-20080027073-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027073-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | HTR6, HTR5A, GPR6 | HTR6 1/4885HTR2C 14/4885ADRA2A 46/4885 |
| US-20100069378-A1 | SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | HTR6, HTR5A, GPR6 | HTR6 1/4885HTR2C 14/4885ADRA2A 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.