Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 7/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326842 | 0.90 | MMP2 (0.44) | SMN1; SMN2MMP2EGFRMEN1MAPT | |
| SCHEMBL7316571 | 0.90 | MMP2 (0.44) | SMN1; SMN2MMP2EGFRMEN1MAPT | |
| SCHEMBL7326943 | 0.90 | MMP2 (0.44) | SMN1; SMN2MMP2EGFRMEN1MAPT | |
| SCHEMBL7324333 | 0.89 | NOS3 (0.45) | MMP2MAPTNOS3NOS1NOS2 | |
| SCHEMBL7321906 | 0.88 | MMP2 (0.43) | MMP2MEN1MAPTKMT2AITGB3 | |
| SCHEMBL7318683 | 0.88 | MMP2 (0.43) | MMP2MEN1MAPTKMT2AITGB3 | |
| SCHEMBL9297123 | 0.87 | NOS3 (0.45) | MMP2EGFRNOS3NOS1NOS2 | |
| Trifluoroacetic Acid SCHEMBL7321835 | 0.85 | MMP2 (0.42) | MMP2MEN1KMT2ANOS3NOS1 | |
| Trifluoroacetic Acid SCHEMBL7317296 | 0.85 | MMP2 (0.42) | MMP2MEN1KMT2ANOS3NOS1 | |
| Trifluoroacetic Acid SCHEMBL7324511 | 0.85 | MMP2 (0.42) | MMP2MEN1KMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | disclosed |