Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 16/20 | 0.55 |
| ▸ | METAP1 | P53582 | 8/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175196 | 1.00 | METAP2 (0.55) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL9514516 | 0.98 | METAP2 (0.53) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL9514519 | 0.98 | METAP2 (0.53) | METAP2METAP1REN | |
| SCHEMBL8209396 | 0.95 | METAP2 (0.49) | METAP2METAP1REN | |
| SCHEMBL13347345 | 0.95 | METAP2 (0.49) | METAP2METAP1REN | |
| SCHEMBL8202433 | 0.95 | METAP2 (0.49) | METAP2METAP1REN | |
| SCHEMBL13430909 | 0.91 | METAP2 (0.45) | METAP2METAP1REN | |
| SCHEMBL10138824 | 0.91 | METAP2 (0.45) | METAP2METAP1REN | |
| Trifluoroacetic Acid SCHEMBL7327225 | 0.90 | METAP2 (0.50) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL27076653 | 0.90 | METAP2 (0.44) | METAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5095119-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-10 | — | — | US | disclosed |
| US-5075451-A | Pyrrolimidazolones useful as renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| US-5064965-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-5023338-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |