Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759384 | 0.91 | ACE (0.76) | ACE | |
| Imidaprilat SCHEMBL683544 | 0.85 | ACE (1.00) | ACE | |
| Imidaprilat SCHEMBL677222 | 0.85 | ACE (1.00) | ACE | |
| Imidaprilat SCHEMBL7338400 | 0.85 | ACE (1.00) | ACE | |
| SCHEMBL683904 | 0.84 | ACE (0.83) | ACE | |
| Imidaprilat SCHEMBL7313750 | 0.84 | ACE (0.98) | ACE | |
| Imidaprilat SCHEMBL7265368 | 0.84 | ACE (0.98) | ACE | |
| Imidaprilat SCHEMBL28579102 | 0.84 | ACE (0.98) | ACE | |
| Imidaprilat SCHEMBL7297440 | 0.84 | ACE (0.98) | ACE | |
| SCHEMBL682416 | 0.82 | ACE (0.80) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274230-B1 | USE OF 2-OXO-IMIDAZOLIDINE DERIVATIVES IN THE PROPHYLAXIS AND TREATMENT OF HEART FAILURE | TANABE SEIYAKU CO., LTD. (JP) | 1992-10-14 | — | — | EP | claimed |