SCHEMBL7328567

SCHEMBL7328567

CC(=O)OC(CO)COP(=O)(O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.58
S1PR1 P21453 1/20 0.47
PRKCA P17252 2/20 0.45
PGK1 P00558 1/20 0.42
PGK2 P07205 1/20 0.42
ENPP2 Q13822 5/20 0.42
LPAR3 Q9UBY5 3/20 0.42
LPAR1 Q92633 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14513725 0.85 PGD (0.58) PGDPGK1PGK2ENPP2LPAR3
SCHEMBL26207056 0.85 PGD (0.58) PGDS1PR1PGK1PGK2ENPP2
SCHEMBL14513716 0.85 PGD (0.58) PGDPGK1PGK2ENPP2LPAR3
SCHEMBL4572660 0.83 PGD (0.56) PGDPGK1PGK2ENPP2LPAR3
SCHEMBL5959432 0.83 PGD (0.56) PGDPGK1PGK2ENPP2LPAR3
SCHEMBL20673 0.82 S1PR1 (0.43) PGDS1PR1PGK1PGK2ENPP2
SCHEMBL17898548 0.80 PGD (0.54) PGDPGK1PGK2ENPP2LPAR3
SCHEMBL11326756 0.80 S1PR1 (0.44) PGDS1PR1PRKCAPGK1PGK2
SCHEMBL16058993 0.79 PGD (0.42) PGDS1PR1PGK1PGK2ENPP2
SCHEMBL9613458 0.79 PGD (0.40) PGDS1PR1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0340759-A1 Salts of O-mono (di)-acetyl-glycero-mono-(bis)-(di)-phosphates of L-acetyl-carnitine and of L-acetyl carnitine esters MAGIS FARMACEUTICI S.p.A. (IT) 1989-11-08 EP claimed
EP-0335396-A1 Glycero-phosphoric and -diphosphoric acids derivatives of L-carnitine or L-carnitine esters MAGIS FARMACEUTICI S.p.A. (IT) 1989-10-04 EP claimed
US-5780617-A PHOSPHORYLATION OF A PHOSPHATIDES WITH A NUCLEOTIDES NEXSTAR PHARMACEUTICALS, INC. (US) 1998-07-14 US disclosed
EP-0531452-A4 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES 1993-06-09 EP disclosed
EP-0531452-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES NeXstar Pharmaceuticals, Inc. (US) 1993-03-17 EP disclosed
WO-1991018914-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES VICAL, INC. (US) 1991-12-12 WO disclosed