Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328567 | 0.79 | PGD (0.58) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL680243 | 0.78 | PGK1 (0.43) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL6924985 | 0.75 | PGK1 (0.39) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL5594382 | 0.72 | ENPP2 (0.50) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL5297305 | 0.72 | PGD (0.45) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL429247 | 0.72 | PGD (0.45) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL19462882 | 0.70 | PGK1 (0.43) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL3447040 | 0.70 | PGK1 (0.43) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL17338080 | 0.70 | PGK1 (0.43) | PGDS1PR1LPAR3ENPP2LPAR1 | |
| SCHEMBL20673 | 0.70 | S1PR1 (0.43) | PGDS1PR1LPAR3ENPP2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2971027-A2 | USE OF PHOSPHOKETOLASE AND PHOSPHOTRANSACETYLASE FOR PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS | Amyris, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144135-A2 | USE OF PHOSPHOKETOLASE AND PHOSPHOTRANSACETYLASE FOR PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS | Amyris, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |