Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7287603 | 0.83 | F2 (0.55) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL4134122 | 0.82 | CA2 (0.64) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL21169926 | 0.82 | PRSS1 (0.49) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL4022608 | 0.80 | PLA2G10 (0.61) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL2699985 | 0.79 | LOXL2 (0.62) | KMT2AALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7149167 | 0.78 | PLA2G10 (0.53) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL9449832 | 0.78 | PLA2G10 (0.53) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL28151928 | 0.78 | PLA2G10 (0.53) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL2643786 | 0.77 | PLA2G10 (0.57) | PLA2G10PLA2G2APRSS1PRSS2PRSS3 | |
| SCHEMBL7134591 | 0.77 | PLA2G10 (0.83) | PLA2G10PLA2G2APARP10CYP17A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343894-B1 | BENZAMIDE PROTEASE INHIBITORS | PFIZER INC. (US) | 1992-06-10 | — | — | EP | disclosed |
| US-4948901-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4948891-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0343894-A1 | Benzamide protease inhibitors | PFIZER INC. (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4874864-A | ANTIPLASMIN, ANTITHROMBIN AGENTS | PFIZER INC. (US) | 1989-10-17 | — | — | US | disclosed |