Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305775 | 0.98 | KDM4E (0.54) | LMNAPOLBKDM1AKDM4EHSD17B10 | |
| SCHEMBL11125142 | 0.82 | KDM4E (0.51) | LMNAPOLBKDM1AKDM4EHSD17B10 | |
| SCHEMBL6157148 | 0.77 | POLB (0.55) | LMNAPOLBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL10471655 | 0.73 | KDM1A (0.43) | LMNAPOLBKDM1AHSD17B10ALDH1A1 | |
| SCHEMBL11797025 | 0.73 | MAPT (0.47) | LMNAKDM1AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3585695 | 0.72 | NPSR1 (0.50) | LMNAALDH1A1TSHRATMMEN1 | |
| Hydrochloric Acid SCHEMBL1010831 | 0.72 | LMNA (0.51) | LMNAPOLBKDM1AALDH1A1HPGD | |
| SCHEMBL830750 | 0.71 | KDM4E (0.74) | LMNAPOLBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9864702 | 0.71 | KMT2A (0.46) | POLBKDM1AKDM4EALDH1A1TSHR | |
| SCHEMBL27604345 | 0.71 | MAPT (0.45) | LMNAPOLBKDM1AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| CN-105073754-B | Aromatic heterocyclic compounds, its manufacturing method and its application | 新日铁住金化学株式会社 | 2018-07-06 | — | — | CN | disclosed |
| US-20160056390-A1 | AROMATIC HETEROCYCLIC COMPOUND, MANUFACTURING METHOD THEREOF, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2016-02-25 | — | — | US | disclosed |
| CN-105073754-A | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | NIPPON STEEL & SUMIKIN CHEM CO | 2015-11-18 | — | — | CN | disclosed |
| WO-1993025528-A1 | NOVEL AMINOPROPANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160056390-A1 | AROMATIC HETEROCYCLIC COMPOUND, MANUFACTURING METHOD THEREOF, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE | PAH, TYR, SLCO2A1 | LMNA 4337/4885POLB 2455/4885KDM1A 415/4885 |
| US-10032993-B2 | Aromatic heterocyclic compound, manufacturing method thereof, organic semiconductor material, and organic semiconductor device | PAH, TYR, SLCO2A1 | LMNA 4337/4885POLB 2455/4885KDM1A 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.