Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606613 | 0.81 | MBTD1 (0.47) | MAPTNPSR1L3MBTL1KMT2ACYP1A2 | |
| SCHEMBL5660735 | 0.78 | HRH3 (0.45) | L3MBTL1ALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL21262607 | 0.78 | FFAR1 (0.43) | MAPTNPSR1KDM4ELMNATDP1 | |
| SCHEMBL5434382 | 0.78 | MAPT (0.50) | CHKAMAPTNPSR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11096322 | 0.76 | MAPT (0.49) | CHKAMAPTNPSR1KDM4ELMNA | |
| SCHEMBL6173007 | 0.76 | SMN1; SMN2 (0.46) | CHKAMAPTNPSR1KDM4ETDP1 | |
| SCHEMBL3166116 | 0.75 | CHKA (0.42) | CHKAMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL27504809 | 0.75 | MEN1 (0.48) | CHKAMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL27504810 | 0.75 | CHKA (0.46) | CHKAMAPTNPSR1LMNATDP1 | |
| SCHEMBL6513376 | 0.75 | PIM1 (0.43) | CHKAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022834-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |