Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21262607 | 0.81 | FFAR1 (0.43) | L3MBTL3L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10606613 | 0.81 | MBTD1 (0.47) | L3MBTL3L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL7328758 | 0.78 | CHKA (0.48) | HRH3L3MBTL1KMT2AUSP2MEN1 | |
| SCHEMBL22816347 | 0.78 | MAOA (0.50) | HRH3KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL19859020 | 0.77 | USP2 (0.49) | L3MBTL3L3MBTL1KMT2AUSP2HPGD | |
| SCHEMBL3174734 | 0.77 | TYMP (0.46) | HRH3CHRNA7 | |
| SCHEMBL22798963 | 0.76 | BRS3 (0.44) | HRH3L3MBTL3L3MBTL1KMT2AUSP2 | |
| SCHEMBL21163358 | 0.76 | FFAR1 (0.48) | HRH3L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28868727 | 0.76 | MAPT (0.42) | L3MBTL3L3MBTL1KMT2AUSP2MEN1 | |
| SCHEMBL8502504 | 0.75 | L3MBTL1 (0.44) | L3MBTL3L3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |