Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6416283 | 0.91 | MMP3 (0.52) | CAPN1MMP3MMP1MMP2 | |
| SCHEMBL6416269 | 0.91 | MMP3 (0.52) | CAPN1MMP3MMP1MMP2 | |
| SCHEMBL7323533 | 0.85 | MMP1 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL7323526 | 0.85 | MMP1 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL10349463 | 0.84 | CAPN1 (0.53) | CAPN1MMP3MMP1MMP2 | |
| SCHEMBL7323409 | 0.83 | MMP1 (0.51) | MMP3MMP1MMP2 | |
| SCHEMBL10349211 | 0.83 | CAPN1 (0.52) | CAPN1MMP3MMP1MMP2 | |
| SCHEMBL7326661 | 0.82 | MMP1 (0.50) | MMP3MMP1MMP2 | |
| SCHEMBL7326667 | 0.82 | MMP1 (0.50) | MMP3MMP1MMP2 | |
| SCHEMBL7321454 | 0.82 | MMP1 (0.50) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |