Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730441 | 0.91 | PTGIR (0.82) | PTGIRPTGDR | |
| SCHEMBL2191945 | 0.90 | PTGIR (1.00) | PTGIR | |
| SCHEMBL2189272 | 0.89 | PTGIR (1.00) | PTGIR | |
| SCHEMBL730250 | 0.88 | PTGDR (0.68) | PTGIRPTGDR | |
| SCHEMBL730780 | 0.88 | PTGDR (0.86) | PTGIRPTGDR | |
| SCHEMBL730530 | 0.87 | PTGIR (0.62) | PTGIRPTGDR | |
| SCHEMBL732822 | 0.87 | PTGIR (0.62) | PTGIRPTGDR | |
| SCHEMBL2216799 | 0.87 | PTGIR (1.00) | PTGIR | |
| SCHEMBL730468 | 0.86 | PTGDR (0.82) | PTGIRPTGDR | |
| SCHEMBL730598 | 0.86 | PTGDR (0.65) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | claimed |
| EP-2177513-B1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-20140357630-A1 | Phenylacetic Acid Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| US-8809524-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20130225808-A1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-8476266-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20130028887-A1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-01-31 | — | — | US | disclosed |
| EP-1666473-B1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8318729-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120094990-A1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-2177513-A1 | PHENYLACETIC ACID COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225808-A1 | PHENYLACETIC ACID COMPOUND | PC, PAH, PDHA2 | PTGIR 3123/4885PTGDR 1630/4885 |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | GPR17, CYSLTR1, KIT | PTGIR 6/4885PTGDR 27/4885 |
| US-20120094990-A1 | PHENYLACETIC ACID COMPOUND | PC, PAH, PDHA2 | PTGIR 3123/4885PTGDR 1630/4885 |
| US-20130028887-A1 | PHENYLACETIC ACID COMPOUND | PC, PAH, PDHA2 | PTGIR 3123/4885PTGDR 1630/4885 |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | GPR17, CYSLTR1, KIT | PTGIR 6/4885PTGDR 27/4885 |
| US-20140357630-A1 | Phenylacetic Acid Compound | PC, PAH, PDHA2 | PTGIR 3123/4885PTGDR 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.