SCHEMBL7328989

SCHEMBL7328989

O=C[C@H]1NCC(=S)C1C(=O)C1=CSC=CN1C(=O)CCCCCC1CCc2ccccc2C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.36
PREP P48147 9/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7490666 0.85 PREP (0.33) PREP
SCHEMBL7488919 0.83
SCHEMBL7330322 0.82
SCHEMBL7321288 0.81 IDH1 (0.33)
SCHEMBL7490329 0.81
SCHEMBL7327936 0.80 GBA1 (0.41) GBA1PREP
SCHEMBL7482921 0.79 PREP (0.35) PREP
SCHEMBL7325498 0.76 PREP (0.42) GBA1PREP
SCHEMBL7318861 0.76
SCHEMBL9047368 0.76 GBA1 (0.42) GBA1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed