SCHEMBL7490666

SCHEMBL7490666

O=C[C@H]1NCC(=S)C1C(=O)C1=CSC=CN1C(=O)CC1Cc2ccccc2C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PREP P48147 8/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7328709 0.87 PREP (0.35) PREP
SCHEMBL7328989 0.85 GBA1 (0.36) PREP
SCHEMBL7482921 0.83 PREP (0.35) PREP
SCHEMBL7321288 0.83 IDH1 (0.33)
SCHEMBL7318772 0.83 GAA (0.32) PREP
SCHEMBL7490329 0.81
SCHEMBL7330322 0.81
SCHEMBL7318861 0.80
SCHEMBL7327641 0.76 PREP (0.42) PREP
SCHEMBL7493407 0.74 PREP (0.33) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed