⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330322 | 0.99 | — | — | |
| SCHEMBL7490329 | 0.97 | — | — | |
| SCHEMBL7482921 | 0.90 | PREP (0.35) | — | |
| SCHEMBL7328989 | 0.83 | GBA1 (0.36) | — | |
| SCHEMBL7490666 | 0.80 | PREP (0.33) | — | |
| SCHEMBL7324555 | 0.78 | HTR1A (0.35) | — | |
| SCHEMBL9049709 | 0.75 | PREP (0.46) | — | |
| SCHEMBL9049670 | 0.74 | PREP (0.47) | — | |
| SCHEMBL7539427 | 0.72 | HTR1A (0.33) | — | |
| SCHEMBL7302389 | 0.72 | PREP (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |