Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.47 |
| ▸ | MMP3 | P08254 | 12/20 | 0.47 |
| ▸ | MMP9 | P14780 | 11/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417587 | 0.94 | MMP1 (0.47) | MMP1MMP3MMP9CYP1B1MMP2 | |
| SCHEMBL9289931 | 0.83 | MMP1 (0.54) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7327878 | 0.83 | MMP1 (0.54) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7321010 | 0.83 | MMP1 (0.54) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7320992 | 0.83 | MMP1 (0.54) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7357542 | 0.82 | MMP1 (0.55) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7329563 | 0.81 | CYP1B1 (0.45) | MMP1MMP3MMP9CYP1B1 | |
| SCHEMBL7357450 | 0.80 | ECE1 (0.51) | MMP1MMP3MMP9 | |
| SCHEMBL7320781 | 0.79 | MMP1 (0.50) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7322384 | 0.75 | MMP1 (0.54) | MMP1MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | claimed |
| US-6340709-B1 | ADMINISTERING BIPHENYLSULFONAMIDE DERIVATIVE | WARNER-LAMBERT COMPANY | 2002-01-22 | — | — | US | disclosed |