Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509082 | 0.86 | HSD11B1 (0.65) | HSD11B1ALDH1A1HTR2AHTR2CHTR7 | |
| SCHEMBL28087584 | 0.85 | HTR2A (0.55) | HSD11B1ALDH1A1HTR2AMGLL | |
| SCHEMBL3391936 | 0.82 | HSD11B1 (0.69) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL6212608 | 0.79 | HSD11B1 (0.74) | HSD11B1ALDH1A1MGLLKDM4EPOLB | |
| SCHEMBL31164032 | 0.79 | HSD11B1 (0.68) | HSD11B1ALDH1A1HTR2AHTR2CHTR7 | |
| SCHEMBL662115 | 0.79 | HSD11B1 (0.68) | HSD11B1ALDH1A1HTR2AHTR2CHTR7 | |
| SCHEMBL14016112 | 0.79 | HSD11B1 (0.69) | HSD11B1ALDH1A1HTR2AHTR2CHTR7 | |
| SCHEMBL27364837 | 0.79 | HSD11B1 (0.63) | HSD11B1ALDH1A1MGLLKDM4EPOLB | |
| SCHEMBL11107232 | 0.78 | HTR2A (0.68) | HSD11B1ALDH1A1HTR2AHTR2CHTR7 | |
| SCHEMBL7408128 | 0.78 | HSD11B1 (0.63) | HSD11B1ALDH1A1HTR2AHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |