Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329052 | 0.85 | HSD11B1 (0.63) | HTR2AMGLLHSD11B1ALDH1A1 | |
| SCHEMBL4500344 | 0.84 | HTR2A (0.56) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL2552838 | 0.82 | HTR2A (0.62) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL7330630 | 0.79 | CPB1 (0.63) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL324342 | 0.79 | HTR2A (0.56) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL18428493 | 0.79 | HTR2A (0.56) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL2556107 | 0.79 | CPB1 (0.67) | HTR2ACPB1KMT2AMEN1MGLL | |
| SCHEMBL462944 | 0.79 | MGLL (0.60) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL11398586 | 0.79 | HTR2A (0.58) | HTR2ACPB1KCNH2KMT2AMEN1 | |
| SCHEMBL2573870 | 0.78 | KMT2A (0.59) | HTR2ACPB1KCNH2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105848483-A | Quinolinyl modulators of roryt | 詹森药业有限公司 | 2016-08-10 | — | — | CN | disclosed |