Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 18/20 | 0.42 |
| ▸ | HTR7 | P34969 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329678 | 0.86 | HTR1A (0.42) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL7334553 | 0.81 | CYP19A1 (0.43) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL7336161 | 0.80 | DRD2 (0.63) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL7326705 | 0.80 | GRIN2B (0.48) | DRD2DRD4DRD3 | |
| SCHEMBL7330680 | 0.80 | HTR1A (0.43) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL7328283 | 0.80 | HTR1A (0.43) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL7329385 | 0.80 | HTR1A (0.43) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL7333718 | 0.79 | DRD2 (0.46) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4210760 | 0.79 | DRD2 (0.61) | DRD2DRD4DRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7334834 | 0.79 | DRD2 (0.61) | DRD2DRD4DRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |