Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.41 |
| ▸ | HTR7 | P34969 | 13/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326173 | 0.89 | CHRM2 (0.43) | HTR1AHTR7 | |
| SCHEMBL7328297 | 0.87 | GRIN1 (0.47) | HTR1AHTR7CXCR4DRD2DRD3 | |
| SCHEMBL7327686 | 0.86 | DRD2 (0.48) | HTR1AHTR7CXCR4DRD2DRD3 | |
| SCHEMBL7335048 | 0.86 | GRIN1 (0.47) | CXCR4DRD2DRD3 | |
| SCHEMBL7327816 | 0.85 | GRIN1 (0.47) | DRD2DRD3 | |
| SCHEMBL7328251 | 0.82 | DRD2 (0.51) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL7334553 | 0.81 | CYP19A1 (0.43) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL7335621 | 0.80 | DRD2 (0.46) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL7328283 | 0.80 | HTR1A (0.43) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL7328268 | 0.79 | DRD2 (0.50) | HTR1AHTR7DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |