Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180493 | 0.84 | GNAI3 (0.45) | GNAI3GNAO1GNAI1SIGMAR1SMN1; SMN2 | |
| SCHEMBL12773927 | 0.83 | SMN1; SMN2 (0.45) | GNAI3GNAO1GNAI1SIGMAR1CHRM5 | |
| SCHEMBL31619612 | 0.83 | GNAI3 (0.41) | GNAI3GNAO1GNAI1SIGMAR1CDK9 | |
| SCHEMBL2922056 | 0.82 | CHRM5 (0.55) | SIGMAR1CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL31465603 | 0.81 | CACNA2D1 (0.44) | SIGMAR1CHRM5CHRM3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4219766 | 0.80 | CHRM5 (0.53) | GNAI3GNAO1GNAI1SIGMAR1CHRM5 | |
| Hydrochloric Acid SCHEMBL8483418 | 0.80 | CHRM5 (0.53) | GNAI3GNAO1GNAI1SIGMAR1CHRM5 | |
| SCHEMBL7933593 | 0.80 | CHRM5 (0.53) | SIGMAR1CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL6887723 | 0.80 | CHRM5 (0.53) | SIGMAR1CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL31216071 | 0.80 | SIGMAR1 (0.43) | SIGMAR1CHRM5CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |