Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330649 | 0.78 | DAO (0.53) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29579885 | 0.75 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4CYP1A2 | |
| SCHEMBL982104 | 0.75 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4CYP1A2 | |
| SCHEMBL9523874 | 0.70 | PDE4A (0.57) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30273068 | 0.69 | DAO (0.46) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL739564 | 0.68 | DAO (0.53) | DAOCYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL736696 | 0.68 | DAO (0.53) | DAOCYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL29446293 | 0.68 | BRD4 (0.49) | DAOMEN1KMT2ADDOGRIN2D | |
| SCHEMBL28721401 | 0.68 | BRD4 (0.49) | DAOMEN1KMT2ADDOGRIN2D | |
| SCHEMBL13015480 | 0.67 | DAO (0.66) | DAOGRIA1MEN1KMT2ADDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |