Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015480 | 0.81 | DAO (0.66) | DAODDOGRIA1ADORA3ADORA2A | |
| SCHEMBL10503087 | 0.81 | PSMB8 (0.60) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1135752 | 0.81 | DAO (0.42) | DAODDOGRIA1GRIA2GRIA3 | |
| SCHEMBL20571788 | 0.78 | GRIA1 (0.38) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1135509 | 0.78 | CYP19A1 (0.45) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7329258 | 0.78 | DAO (0.49) | DAODDOGRIA1GRIA2GRIA3 | |
| SCHEMBL7319991 | 0.77 | KIF11 (0.38) | GRIA1GRIA2GRIA3GRIA4ADORA3 | |
| Bromide SCHEMBL5097394 | 0.73 | DAO (0.46) | DAODDOGRIA1ADORA3ADORA2A | |
| SCHEMBL29580191 | 0.72 | PSMB8 (0.55) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4706735 | 0.72 | PSMB8 (0.55) | DAOGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |