Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7323588 | 0.99 | HRH3 (0.46) | HRH3LTA4HDPP4KCNA3PLA2G2A | |
| SCHEMBL7323953 | 0.96 | HRH3 (0.48) | HRH3LTA4HDPP4PLA2G2ACACNA1B | |
| Hydrochloric Acid SCHEMBL7329990 | 0.95 | HRH3 (0.47) | HRH3LTA4HDPP4PLA2G2ACACNA1B | |
| SCHEMBL7321121 | 0.92 | LTA4H (0.48) | HRH3LTA4HPLA2G2A | |
| Hydrochloric Acid SCHEMBL7330696 | 0.91 | LTA4H (0.47) | HRH3LTA4HPLA2G2A | |
| SCHEMBL7328652 | 0.83 | LTA4H (0.46) | HRH3LTA4H | |
| Hydrochloric Acid SCHEMBL7322738 | 0.82 | LTA4H (0.45) | HRH3LTA4H | |
| SCHEMBL7330957 | 0.79 | LTA4H (0.50) | LTA4H | |
| SCHEMBL7330776 | 0.79 | LTA4H (0.53) | HRH3LTA4H | |
| SCHEMBL7329701 | 0.79 | LTA4H (0.50) | HRH3LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625979-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015073-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |