Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | GABRP | O00591 | 3/20 | 0.52 |
| ▸ | GABRD | O14764 | 3/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.52 |
| ▸ | GABRE | P78334 | 3/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11825759 | 0.87 | CHRM1 (0.74) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7320356 | 0.84 | ALOX12 (0.77) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7321452 | 0.84 | CHRM1 (1.00) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7330628 | 0.84 | ALOX12 (1.00) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11384670 | 0.82 | ALOX12 (0.77) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7319957 | 0.81 | SMN1; SMN2 (0.77) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11826679 | 0.81 | ALOX12 (0.77) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL3825546 | 0.80 | ALOX12 (0.70) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11828237 | 0.80 | CHRM1 (0.71) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL10404819 | 0.79 | ALOX12 (0.72) | CHRM1ALOX12SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902794-A | Triazolo-benzodiazepines | THE UPJOHN COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4010177-A | [3-Substituted-5-[(di-methylamino)methyl]-4H-1,2,4-triazol-4-yl]benzophenones and process | THE UPJOHN COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
| US-3992408-A | CHEMICAL INTERMEDIATES | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3987052-A | SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3933794-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |