Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | GABRP | O00591 | 2/20 | 0.55 |
| ▸ | GABRD | O14764 | 2/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.55 |
| ▸ | GABRE | P78334 | 2/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330628 | 0.87 | ALOX12 (1.00) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL3821334 | 0.86 | ALOX12 (0.70) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL11384670 | 0.85 | ALOX12 (0.77) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL7320356 | 0.85 | ALOX12 (0.77) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL16144652 | 0.85 | GABRA1 (0.77) | SMN1; SMN2ALOX12CHRM1GABRA1GABRA5 | |
| SCHEMBL11826679 | 0.85 | ALOX12 (0.77) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL11826478 | 0.84 | CHRM1 (0.72) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL7323866 | 0.83 | CHRM1 (1.00) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL7329432 | 0.81 | CHRM1 (0.72) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM | |
| SCHEMBL10404819 | 0.81 | ALOX12 (0.72) | SMN1; SMN2ALOX12CHRM1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987052-A | SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |