Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 9/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 5/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7321899 | 0.95 | HTRA1 (0.41) | NOS2MMP2HDAC1MAOBHTRA1 | |
| SCHEMBL7326943 | 0.89 | MMP2 (0.44) | NOS2MMP2EGFRHTRA1 | |
| SCHEMBL7326842 | 0.89 | MMP2 (0.44) | NOS2MMP2EGFRHTRA1 | |
| SCHEMBL7316571 | 0.89 | MMP2 (0.44) | NOS2MMP2EGFRHTRA1 | |
| Trifluoroacetic Acid SCHEMBL7317296 | 0.84 | MMP2 (0.42) | NOS2MMP2HTRA1 | |
| Trifluoroacetic Acid SCHEMBL7324511 | 0.84 | MMP2 (0.42) | NOS2MMP2HTRA1 | |
| Trifluoroacetic Acid SCHEMBL7321835 | 0.84 | MMP2 (0.42) | NOS2MMP2HTRA1 | |
| SCHEMBL9724536 | 0.83 | TDP1 (0.51) | NOS2HDAC1EGFRHTRA1 | |
| SCHEMBL7315631 | 0.82 | ITGB3 (0.50) | — | |
| SCHEMBL7328326 | 0.81 | MMP2 (0.53) | NOS2MMP2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | disclosed |